High-Performance Bioinformatics for Sustainable Agriculture & Industrial Biotechnology
Zynt Bio delivers cloud-native, high-performance computational genomics services optimized exclusively for plant systems, environmental microbiomes, and industrial biomanufacturing. By deploying containerized Nextflow workflows on AWS, we deliver reproducible, audited, and scalable data processing.
High-resolution mapping, quantification, and profiling of coding and non-coding RNA dynamics to capture gene expression shifts with absolute clarity.
Differential Gene Expression (DGE): High-throughput transcript abundance estimation and statistical modeling across complex multi-factor experimental designs.
Small RNA & RNA Interference (RNAi) Profiling: Precise identification, size distribution analysis, and target prediction for regulatory sRNA and silencing constructs.
Functional Enrichment: GO terms, KEGG pathways, and metabolic network mapping to translate raw differential counts into biological insights.
Specialized workflows designed to separate host, vector, and microbial sequence profiles in mixed infections, decoupling plant immune responses from pathogen virulence.
Dual RNA-Seq Processing: Simultaneous host-pathogen alignment and transcript de-convolution to decouple immunity responses from virulence factors.
Shotgun and amplicon workflows for highly diverse soil and plant-associated microbiomes, reconstructing community genomes and taxonomic structure from complex environmental samples.
Shotgun Metagenomics & MAG Binning: High-throughput assembly and advanced binning (MetaBAT2/MaxBin2) to reconstruct high-quality Metagenome-Assembled Genomes from soil or plant-associated microbiomes.
High-Throughput Amplicon Sequencing: Optimized, cost-efficient taxonomic profiling using 16S, ITS, and 18S target regions.
Tailored for synthetic biology, crop-protection R&D, and biomanufacturing organizations looking to audit genomic stability and engineering accuracy.
Whole-Genome Resequencing & Variant Calling: High-coverage alignment to detect SNPs, indels, and structural variations in engineered production clones.
CRISPR/Cas9 Off-Target Screening: Rigorous genome-wide scanning to catch unintended insertions, deletions, or structural modifications.
Expression Cassette Integrity Audits: Specialized verification to ensure synthetic constructs, plasmids, and integrated cassettes match exact design specs without rearrangements.
De Novo Reference Assembly: Full structural reconstruction and functional annotation of novel microbial isolates or complex crop lines.
Comprehensive Synthesis Portfolio: A clear executive and technical report interpreting the biological relevance, metabolic impacts, and actionable outcomes of your dataset.
Technical Methodology & IP Documentation: A rigorous, formal narrative detailing exact computational steps, database versions, and command-line parameters.
Standardized R&D Methods Reporting: A detailed report breaking down data ingestion criteria, alignment constraints, and statistical validation thresholds.
Auditable Nextflow Traceability Logs: Full workflow metadata — container hashes, software version pinning, and time-stamped execution logs.
Secure Cloud Storage Assets: Cleaned FASTQ files, BAM alignments, quantified count matrices, and high-resolution figures safely archived in an isolated Amazon S3 bucket, accessible exclusively by your organization.